Generally, immortality is the concept of living for an indefinite length of time, presumably in a perpetual healthy state, unless suffering a violent death.
In the works of J.R.R. Tolkien, only beings of Arda such as the Ainur (including Wizards) and Elves are immortal. The state of Orcs' lives is unknown. Men, Dwarves, Hobbits and most other races cannot live forever and thus are subject to aging and natural death however various members of those races have endured longer extended lifespans beyond normal constraints through various means. In Tolkien's universe, despite many having a desire for it, immortality is not desirable for those who are of mortal kind. Every race has a set span; to exceed this span proves to be agony for mortals. There are many examples of this throughout his work: the kings of Numenor who became witless and agonized by attempting to cling to life as long as possible (as opposed to earlier kings who gave up their lives willingly); Gollum's transformation into a twisted and starved thing after having his life extended nearly 5 times longer than it should have been via the One Ring; Bilbo's comment on his 111th birthday about feeling "thin and stretched", like "butter being spread on too much bread", this also being an effect of the One Ring. The only time mortals have ever been accorded peace in immortality is when they are accounted of the Elves: this choice has been mostly restricted to the Peredhil, the Half-Elven (the one known exception to this being Tuor, who was born a full-blooded Man but was given the choice to be accounted among the Eldar).
The Army of the Dead was cursed by Isildur with immortality in form of an existence as undead skeletons after they abandoned their oath in the War of the Last Alliance. Their only chance of dying was to fulfill their oath.
In the latter half of the Second Age, Sauron's corruption of the Numenorean King Ar-Pharazôn made him believe that if he could invade and conquer the Blessed Land, he could become immortal, resulting in the destruction of Numenor and Ar-Pharazôn's imprisonment.